任秋实

生物医学工程教授 实验室负责人, 博士生导师


信息与工程学部 副主任


联系电话:
电子邮箱:renqsh@coe.pku.edu.cn
个人主页:http://www.milab.wiki/



学术经历:

1985-1987 俄亥俄州立大学电机系硕士
1987-1990 俄亥俄州立大学电机系博士
1991-1994 迈阿密大学生物医学工程系助理教授
2002-2009 上海交通大学生物医学工程系教授
2009-至今 云顶娱乐生物医学工程系教授

 

研究领域:

分子影像技术与装备研究、视觉科学与诊疗技术研究、分子影像应用与探针研发

 

背景资料:

长期从事分子医学影像技术与设备,眼科与视觉光学,激光与光子生物医学,神经医学工程研究。

在分子影像研究领域,主要探索分子医学影像成像理论,成像方法,关键技术,研发分子医学影像集成装备,研究分子医学影像新型探针。先进水平的小动物多模态分子影像设备,可以实现同机,实时,活体的四模态成像,可为反射和光学标记的分子探针研发提供精确,可定量的多模态融合成像结果,并探索四模态分子影像设备在个性化癌症诊断与治疗中的应用,使用多模态,多标记手段,对癌症进行精确分型及个性化治疗。

在视觉科学与诊疗技术研究领域,主要开展激光医学与视觉光学的基础理论及相关技术的研究,替代激光技术对皮肤胶原组织再生与再生的替代机制,研究角膜组织对各种不同激光波长的生物组织学反应,为激光屈光手术的临床应用规模基础;围绕着视觉光学及视觉信息处理若干前沿关键问题,提出由视神经作为视觉假体与视觉传递的神经接口,利用可植入式微电极阵列来进行视觉修复及视力矫正的新方法。

发表学术论文300余篇,获美国专利2项,国际授权专利3项,国内授权专利40余项。当选美国生物与医学工程学会会士(AIMBE Fellow),国际光学学会会士(SPIE Fellow)。

 

获得荣誉:

国家自然科学基金委分子影像创新群体负责人2014
国家重大科学仪器设备开发专项首席科学家2011
国家重点基础研究发展计划(973计划)首席科学家2006年,2011年
教育部长江学者特聘教授2007
国家杰出青年基金2006

 

发明专利:

美国发明专利:
US Patent No: 5423800: Laser Sclera Buckling for Retinal Detachment Surgery: Method and Device. Issue Date: June 13, 1995.
中国发明专利:
共聚焦内窥镜微小镜显微镜探头. 专利号:ZL200510029661.8
成像光纤束与扫描光学系统耦合的光学系统.  专利号:ZL 200510029660.3
植入式可编程神经刺激器.专利号:200610025658.3
用于视觉假体的眼内摄像头.  专利号:200610027984.8
基于微光机电系统的可调节人工晶体.专利号:200610024505.7
超极化惰性气体核磁共振系统性能测试装置. 专利号:200510110654.0

 

主要论文列表:

  1. Zhiming Li, Peng Huang, Xuejun Zhang, Jing Lin, Sen Yang, Bing Liu, Feng Gao, Peng Xi, Qiushi Ren, Daxiang Cui. RGD-conjugated dendrimer-modified gold nanorods for in vivo tumor targeting and photothermal therapy. MOLECULAR PHARMACEUTICS7 (1):94-104, 2010.
  2. Teng Luo, Peng Huang, Guo Gao, Guangxia Shen, Shen Fu, Daxiang Cui, Chuanqing Zhou, and Qiushi Ren. Mesoporous silica-coated gold nanorods with embedded indocyanine green for dual mode X-ray CT and NIR fluorescence imaging. Optics Express, 19(18): 17030-17039, 2011.
  3. Xu W, Luo T, Li P, Zhou C, Cui D, Pang B, Ren Q, Fu S. RGD-conjugated gold nanorods induce radiosensitization in melanoma cancer cells by downregulating αvβ3 expression. International Journal of Nanomedicine. 7:915-924, 2012.
  4. Xu W, Luo T, Pang B, Li P, Zhou C, Huang P, Zhang C, Ren Q, Fu S. The radiosensitization of melanoma cells by gold nanorods irradiated with MV X-ray. Nano Biomed Eng. 4:6-11, 2012.
  5. Qiushi Zhang, Yanye Lu, Kun Yang, Qiushi Ren, Position mapping and a uniformity correction method for small-animal SPECT based on connected regional recognition, Nucl Instrum Meth A. 2013;704:1-6.
  6. Zhang, Q., Lu, Y., Yang, K., & Ren, Q. (2013). Position mapping and a uniformity correction method for small-animal SPECT based on connected regional recognition. Nuclear Instruments & Methods in Physics Research, 704(4), 1–6.
  7. Zhang, Q., Zhang, C., Lu, Y., Yang, K., & Ren, Q. (2013). Progress in the development of CdZnTe unipolar detectors for different anode geometries and data corrections. Sensors, 13(2), 2447.
  8. Li, S., Zhang, Q., Xie, Z., Liu, Q., Xu, B., Yang, K. & Ren, Q, et al. (2015). Gate simulation of a lyso-based spect imager: validation and detector optimization. Nuclear Instruments & Methods in Physics Research, 773(773), 21-26.
  9. Lu, Y., Yang, K., Zhou, K., Zhang, Q., Pang, B., & Ren, Q. (2014). Development of a SiPM-based PETimaging system for small animals. Nuclear Instruments & Methods in Physics Research, 743(8), 30–38.
  10. Wang, H., Sun, H., Wei, H., Xi, P., Nie, S., & Ren, Q. (2014). Biocompatible hyaluronic acid polymer-coated quantum dots for Cd44+ cancer cell-targeted imaging. Journal of Nanoparticle Research, 16(10), 1-13.
  11. Wang, G., Zhang, B., Ding, Y., He, Y., Chen, J. Lu, Y., & Ren, Q. et al. (2015). A modularly designed fluorescence molecular tomography system for multi-modality imaging. Journal of X-ray science and technology, 23(2), 147-56.
  12. Li, S., Zhou, K., Zhang, Q., Zhang, J., Yang, K., & Xu, B., & Ren, Q et al. (2015). Performance tests for Ray-Scan 64 PET/CT based on NEMA NU-2 2007. Journal of Instrumentation, 10(3), P03016-P03016.
  13. Vuletic, I., Liu, J., Wu, H., Ding, Y., Yu, L., & Li, C., & Ren, Q et al. (2015). Establishment of an mkate2-expressing cell line for non-invasive real-time breast cancer in vivo imaging. Molecular Imaging & Biology, the Official Publication of the Academy of Molecular Imaging, 17(6), 811.
  14. Zhou K, Tian J, Meng X, Yang K, Xu B, Yang Z, Ren Q. A Novel Scatter Correction Method for Cone-Beam Computed Tomography [J]. Journal of Computer Assisted Tomography, 2016, 40(4): 632-8.
  15. Zhou K, Huang Y, Meng X, Li Z, Li S, Yang K, Ren Q. A New Method for Cone-Beam Computed Tomography Geometric Parameters Estimation [J]. Journal of Computer Assisted Tomography, 2016, 40(4): 639-48.
  16. Xie, Z., Li, S., Yang, K., Xu, B., & Ren, Q. (2016). Evaluation of a wobbling method applied to correcting defective pixels of CZT detectors in SPECT imaging. Sensors, 16(6), 772.
  17. Vuletic I, Zhou K, Li H, Bai H, Meng X, Zhu S, Ding Y, Li J, Sun H, Ren Q. Validation of Bevacizumab Therapy Effect on Colon Cancer Subtypes by Using Whole Body Imaging in Mice [J]. Molecular Imaging and Biology, 2017, 19(6): 847-56.
  18. Xie Q, Zhu H, Wang F, Meng X, Ren Q, Xia C, Yang Z. Establishing Reliable Cu-64 Production Process: From Target Plating to Molecular Specific Tumor Micro-PET Imaging. Molecules. 2017; 22(4):641.
  19. Xie ZH, Li SY, Zhou K, Vuletic I, Meng XX, Zhu SH, Xu H, Yang K, Xu BX, Zhang JM, Ren QS. PKU-PET-II: A novel SiPM-based PET imaging system for small animals [J]. Nucl Instrum Methods Phys, 2018, 877(104-11).
  20. Yanye Lu, Markus Kowarschik, Xiaolin Huang, Shuqing Chen, Qiushi Ren, Rebecca Fahrig, Joachim Hornegger and Andreas Maier. Material Decomposition Using Ensemble Learning for Spectral X-ray Imaging. IEEE Transactions on Radiation and Plasma Medical Sciences, vol. 2, no. 3, pp. 194-204, 2018.
  21. Yanye Lu, Markus Kowarschik, Xiaolin Huang, Yan Xia, Jang-Hwan Choi, Shuqing Chen, Shiyang Hu, Qiushi Ren, Rebecca Fahrig, Joachim Hornegger and Andreas Maier. A Learning-based Material Decomposition Pipeline for Multi-energy X-ray Imaging. Medical Physics, vol. 46, no. 2, pp. 689-703, 2019
  22. Xiangxi Meng, Yi Du, Ruoxi Wang, Ziyuan Li, Sihao Zhu, Hao Wu, Changhui Li, Weiqiang Chen, Shuming Nie, Qiushi Ren, Yanye Lu. Cherenkov Excited Luminescence Imaging Induced by Megavolt X-ray Beams in the Second Near-Infrared Window. Optics Communications, 2019;145:417-421

Vision and Ophthalmic Technology

  1. Q.S. Ren, R.P. Gailitis, K.P. Thompson, and J.T. Lin. Ablation of the Cornea and Synthetic Collagen Using a UV (213nm) Solid State Laser. IEEE J. Quant. Electron. Special Issue on Lasers in Medicine and Biology, 26:2284-2288, 1990.
  2. Q.S. Ren, and R. Birngruber. Axicon: A New Laser Beam Delivery System for Cornel Sugery. IEEE J. Quant. Electron. Special Issue on Lasers in Medicine and Surgery, 26:2305-2308, 1990.
  3. Q.S. Ren, V. Venugopalan, K. Schomaker, T.F. Deutsch, T.J. Flott, C.A. Puliafito, R. and Birngruber. Mid-Infrared Laser Ablation of the Cornea: A Comparative Study. Lasers in Surgery and Medicine, 12:274-281, 1992.
  4. G Simon, RH Small, QS Ren, and JM Parel. Effect of Corneal Hydration on Goldmann Applanation Tonometry and Corneal Topography. Refractive and Corneal Surgery, 9:110-117, 1993.
  5. QS Ren, G Simon, JM Parel, J.M. Parel and Smiddy W. Laser Scleral Buckling For Retinal Reattachment. Am. J. Ophthalmol, 115:758-762, 1993.
  6. QS Ren, G Simon, JM Parel. Ultraviolet Solid-State Laser (213-nm) Photorefractive Keratectomy: In Vitro Study. Ophthalmology, 100:1828-1834, 1993.
  7. QS Ren, G Simon, JM Legeais, JM Parel, W Culbertson, JH Shen, Y Takesue, M Savoldelli. Ultraviolet  Solid-State Laser (213-nm) Photorefractive Keratectomy: In Vivo Study. Ophthalmology, 101:883-889, 1994.
  8. QS Ren, Simon G, Parel JM. Noncontact Laser Photothermal Keratoplasty III: Histolopathological Study in Animal Eyes. J. Refract Corneal Surg. 10:529-539, 1994.
  9. QS Ren, RH Keates, A Hill, Berns M. Laser Refractive Surgery: A Review and Current Status. Opt. Eng.,34: 642-660, 1995.
  10. Hong Guo, Nina Korablinova, Qiushi Ren, Josef Bille. Wavefront reconstruction with artificial neural networks. Optics Express, 14 (14): 6456-6462, 2006.
  11. Chuanqing ZhouXinyu Chai, Li Yuan and Yanling He, Qiushi Ren. Corneal High-Order Aberration after Aberration-free Aspheric Ablation and Conventional Ablation for Myopic Correction. Current Eye Research, 32(5):431-438, 2007.
  12. Chuanqing Zhou, Min Jin, Xiaoyuan Wang, Qiushi Ren. Corneal Wavefront-guided Ablation With the Schwind ESIRSIS laser for myopia. Journal of Refractive Surgery, 23(6):573-580, 2007.
  13. Zhou Chuanqing, Wang Weichao, Yang Kun, Chai Xinyu, Ren Qiushi. Measurement and comparison of the optical performance of an ophthalmic lens based on a Hartmann-Shack wavefront sensor in real viewing conditions. Applied Optics, 47(34): 6434-6441, 2008.
  14. Yu Xia, Xinyu Chai, Chuanqing Zhou, Qiushi Ren. Corneal nerve morphology and sensitivity changes after ultraviolet A/riboflavin treatment. Experimental Eye Research, 93(4):541-7, 2011.
  15. Xia Y, Tao C, Zhou C, Ren Q. Synergistic Effects of Ultraviolet A/Riboflavin and Glucose on Corneal Collagen Cross-linking. Journal of Refractive Surgery. 2011; 27:216-222
  16. Cuixia Dai, Chuanqing Zhou, Shanhui Fan, Zhe Chen, Xinyu Chai, Qiushi Ren, and Shuliang Jiao. Optical coherence tomography for whole eye segment imaging. Optics Express, Vol. 20, Issue 6, pp. 6109-6115, 2012.
  17. Tao, C., Han, Z., Sun, Y., Zhou, C., Roberts, C. J., & Zhou, D., Ren, Q. (2013). Corneal hysteresis with intraocular pressure of a wide range: a test on porcine eyes. Journal of Refractive Surgery, 29(12), 850-854.
  18. Tao, C., Sun, Y., Zhou, C., Han, Z., & Ren, Q. (2013). Effects of collagen cross-linking on the interlamellar cohesive strength of porcine cornea. Cornea, 32(2), 169-73.
  19. Han, Z., Sui, X., Zhou, D., Zhou, C., & Ren, Q. (2013). Biomechanical and refractive behaviors of keratoconic cornea based on three-dimensional anisotropic hyperelastic models. Journal of Refractive Surgery, 29(4), 282-290.
  20. Sun, Y., Fan, S., Zheng, H., Dai, C., Ren, Q., & Zhou, C. (2014). Noninvasive imaging and measurement of accommodation using dual-channel SD-OCT.  Current Eye Research, 39(6), 611.
  21. Han, Z., Tao, C., Zhou, D., Sun, Y., Zhou, C., & Ren, Q., et al. (2014). Air puff induced corneal vibrations: theoretical simulations and clinical observations. Journal of Refractive Surgery, 30(3), 208-213.
  22. Fan, S., Sun, Y., Dai, C., Zheng, H., Ren, Q., & Jiao, S., et al. (2014). Accommodation-induced variations in retinal thickness measured by spectral domain optical coherence tomography. Journal of Biomedical Optics, 19(9), 96012.
  23. Wu, N., Ye, S., Ren, Q., & Li, C. (2014). High-resolution dual-modality photoacoustic ocular imaging. Optics Letters, 39(8), 2451.
  24. Fan, S., Lin, L., Qian, L., Dai, C., Ren, Q., & Jiao, S., et al. (2015). Dual band dual focus optical coherence tomography for imaging the whole eye segment. Biomedical Optics Express, 6(7), 2481.
  25. Li P, Huang Z, Yang S, Liu X, Ren Q. Adaptive classifier allows enhanced flow contrast in OCT angiography using a histogram-based motion threshold and 3D Hessian analysis-based shape filtering [J]. Optics Letter, 2017, 42(23): 4816-9.
  26. Zekuan Yu, Qing Xiang, Jiahao Meng, Caixia Kou, Qiushi Ren, Yanye Lu. Retinal Image Synthesis from Multiple-Landmarks Input with Generative Adversarial Networks. Biomedical Engineering Online. 2019;18(1):62.
  27. Xi Liu, Zhiyu Huang, Zhenzhou Wang, Chenyao Wen, Zhe Jiang, Zekuan Yu, Jingfeng Liu, Gangjun Liu, Xiaolin Huang, Andreas Maier, Qiushi Ren, Yanye Lu. A Deep Learning Based Pipeline for Optical Coherence Tomography Angiography. Journal of Biophotonics, 2019; 12:e201900008.
  28. Bin Qiu, Zhiyu Huang, Xi Liu, Xiangxi Meng, Yunfei You, Gangjun Liu, Kun Yang, Andreas Maier, Qiushi Ren, Yanye Lu. Noise Reduction in Optical Coherence Tomography Images Using a Deep Neural Network with Perceptually-Sensitive Loss Function. Biomedical Optics Express, Vol. 11, Issue 2, pp. 817-830, 2020
  29. Zhe Jiang, Zhiyu Huang, Bin Qiu, Xi Liu, Xiangxi Meng, Yunfei You, Gangjun Liu, Chuanqing Zhou, Kun Yang, Andreas Maier, Qiushi Ren, Yanye Lu. A Comparative Study of Deep Learning Models for Optical Coherence Tomography Angiography. Biomedical Optics Express, Accepted

Visual Prosthesis for Blindness

  1. Xinyu Chai, Liming Li, Kaijie Wu, Chuanqing Zhou, Pengjia Cao, Qiushi Ren. C-Sight Visual Prostheses for the Blind:Optic nerve stimulation with penetrating electrode array. IEEE Engineering in Medicine and Biology Magazine, 2008, 27(5):20-28.
  2. Liming Li, Pengjia Cao, Mingjie Sun, Xinyu Chai, Kaijie Wu, Xun Xu, Xiaoxin Li, Qiushi Ren. Intraorbital optic nerve stimulation with penetrating electrodes: in vivo electrophysiology study in rabbits. Graefes Arch Clin Exp Ophthalmol, 247(3):349-361, 2009.
  3. C S Cai, L M Li, X L Li, P P Chen, X Y Chai and Q S Ren. Response properties of electrically evoked potential elicited by multi-channel penetrative optic nerve stimulation in rabbits. Doc Ophthalmol, 118:191-204, 2009.
  4. Xiaoliang Li, Changsi Cai, Liming Li, Xinyu Chai, Qiushi Ren. A Low-Hemorrhage-Risk Surgical Approach to Expose the Optic Nerve in Rabbits without Bony Removal and Rectus Resection. Veterinary Ophthalmology, 12(4):227-233, 2009.
  5. Leilei Zhang, Xinyu Chai, Shu Ling, Jin Fan, Kun Yang, Qiushi Ren. Dispersion and Accuracy of Simulated Phosphene Positioning Using Tactile Board. Artificial Organs, 33(12):1109-1116, 2009.
  6. Zhou Hong-Bo, Li Gang, Sun Xiao-Na, Zhu Zhuang-Hui, Jin Qing-Hui, Zhao Jian-Long, Ren Qiu-ShiIntegration of Au Nanorods With Flexible Thin-Film Microelectrode Arrays for Improved Neural InterfacesJournal of Microelectromechanical Systems, 18(1):88-96, 2009.
  7. Zhou Hong-Bo, Li Gang, Sun Xiao-Na, Zhu Zhuang-Hui, Lou Xin-Hui, Zhang Hua, Liang Ting, Jin Qing-Hui, Zhao Jian-Long, Ren Qiu-Shi. Fabrication of Pyramid-Shaped Three-Dimensional Flexible Microelectrode Array for Improved Neural Interfacing. Sensor Letters, 7(1), pp 96-103, 2009.
  8. Chuanqing Zhou, Chen Tao, Xinyu Chai, Yong Sun, and Qiushi Ren. Implantable Imaging System for Visual Prosthesis. Artificial Organs, 34(6):518-522, 2010.
  9. Jingjing Sun, Yiliang Lu, Pengjia Cao, Xiaoliang Li, Changsi Cai, Xinyu Chai, Qiushi Ren, and Liming Li. Spatiotemporal Properties of Multi-peaked Electrically Evoked Potentials Elicited by Penetrative Optic Nerve Stimulation in Rabbits. Invest Ophthalmol Vis Sci., 52 (1):146-154, 2011
  10. Ying Zhao, Yanyu Lu, Cong Dai, Chuanqing Zhou, Qiushi Ren, Xinyu Chai. Chinese character recognition using simulated phosphene maps. Investigative Ophthalmology & Visual Science (IOVS), 2011, 52(6):3404-3412.
  11. Changsi Cai, Qiushi Ren, Neal J. Desai, Joseph F. Rizzo III, and Shelley I. Fried. Response variability to high rates of electric stimulation in retinal ganglion cells. Journal of Neurophysiology, 106(1):153-162, 2011.
  12. Yanyu Lu, Jin Fan, Chuanqing Zhou, Ying Zhao, Cong Dai, Chen Tao, Qiushi Ren, Xinyu Chai. Estimating the position of simulated phosphenes using a tactile guide. Seeing and Perceiving, 24(2) 125-140, 2011.
  13. Ying Zhao, Yanyu Lu, Ji Zhao, Kaihu Wang, Qiushi Ren, Kaijie Wu, Xinyu Chai. Reading Pixelized Paragraphs of Chinese Characters using Simulated Prosthetic Vision.      Investigative Ophthalmology & Visual Science (IOVS), 52(8):5987-5994, 2011.
  14. Yiliang Lu, Pengjia Cao, Jingjing Sun, Jing Wang, Liming Li, Qiushi Ren, Yao Chen, Xinyu Chai. Using independent component analysis to remove artifacts in visual cortex responses elicited by electrical stimulation of the optic nerve. Journal of Neural Engineering, 9(2) : 026002, 2012.
  15. Sui X, Sun J, Li L, Zhou C, Luo X, Xia N, Yan Y, Chen S, Ren Q, Chai X. Evaluation of a MEMS-based dual metal-layer thin-film microelectrode array for suprachoroidal electrical stimulation. IEEE Trans Neural Syst Rehabil Eng. 2012, 21(4): 524-531 .
  16. Liang T, Zhao L, Sui X, Zhou C, Ren Q, Qi Y. Threshold Suprachoroidal-Transretinal Stimulation Current Required by Different-Size Electrodes in Rabbit Eyes. Ophthalmic Res. 45:113-121, 2011.
  17. Liu W, Song Z, Mo Y, Wang W, Sui X, Gong Y, Jiang Y, Zhang Y, Huang J, Gu Q, Li G, Zhou C, Yu Z, Ren Q, Sun X, Wang F. In vitro Biocompatibility of a Platinum-Electrode Embedded Photosensitive Polyimide (Durimide) Retinal Prosthesis. Current Eye Resesarch. 37:1036-1044, 2012.
  18. Li M, Yan Y, Wang Q, Zhao H, Chai X, Sui X, Ren Q. A simulation of current focusing and steering with penetrating optic nerve electrodes. J Neural Eng, 2013, 10(6): 066007
  19. Lu Y, Yan Y, Chai X, Ren Q, Chen Y. Electrical stimulation with a penetrating optic nerve electrode array elicits visuotopic cortical responses in cats. J Neural Eng, 2013, 10(3): 036022
  20. Sun J, Chen Y, Chai X, Ren Q. Penetrating electrode stimulation of the rabbit optic nerve: parameters and effects on evoked cortical potentials. Graefes Arch Clin Exp Ophthalmol, 2013, 251(11): 2545-54
  21. Yanyu Lu, Han Kan, Jie Liu, Jing Wang, Chen Tao, Yao Chen, Jie Hu, Qiushi Ren, Xinyu Chai. Optimizing Chinese characters display for improving the performance of recognition and reading under simulated irregular phosphene maps. Invest. Ophthalmol. Vis. Sci. 2013, 54(4):2918-2926.
  22. Sui XH, Sun JJ, Li LM, Zhou CQ, Luo XJ, Xia NS, Yan Y, Chen Y, Ren QS, Chai XY. Evaluation of a MEMS-based dual metal-layer thin-film microelectrode array for suprachoroidal electrical stimulation. IEEE Trans. Neur. Sys. Rehab. Eng., 2013, 21(4): 524-531
  23. Li, S., Hu, J., Chai, X., Ren, Q., & Peng, Y. (2012). Research on and design of visual prosthesis based on visual information processing. Journal of Biomedical Engineering, 29(4), 754.
  24. Lu, Y., Cao, P., Sun, J., Wang, J., Li, L., & Ren, Q., et al. (2012). Using independent component analysis to remove artifacts in visual cortex responses elicited by electrical stimulation of the optic nerve. Journal of neural engineering, 9(2), 026002.
  25. Xia Y, Peng X, Ren Q. Retinitis pigmentosa patients' attitudes toward participation in retinal prosthesis trials[J]. Contemporary Clinical Trials, 2012, 33(4):628.
  26. Lu, Y., Yan, Y., Chai, X., Ren, Q., Chen, Y., & Li, L. (2013). Electrical stimulation with a penetrating optic nerve electrode array elicits visuotopic cortical responses in cats. Journal of Neural Engineering, 10(3), 036022.
  27. Jiang, X., Sui, X., Lu, Y., Yan, Y., Zhou, C., & Li, L., Ren, Q. (2013). In vitro and in vivo evaluation of a photosensitive polyimide thin-film microelectrode array suitable for epiretinal stimulation. Journal of Neuroengineering & Rehabilitation, 10(1), 48.
  28. Li, M., Yan, Y., Wang, Q., Zhao, H., Chai, X., & Sui, X., Ren, Q. (2013). A simulation of current focusing and steering with penetrating optic nerve electrodes. Journal of Neural Engineering, 10(6), 066007-066007.
  29. Sui, X., Sun, J., Li, L., Zhou, C & Ren, Q. (2012). Evaluation of a MEMS-based dual metal-layer thin-film microelectrode array for suprachoroidal electrical stimulation[J]. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2012, 21(4): 524-531.
  30. Yu X, Ren Q. Ethical Considerations for Volunteer Recruitment of Visual Prosthesis Trials[J]. Science & Engineering Ethics, 2012, 19(3):1099-1106.
  31. Lu, Y., Kan, H., Liu, J., Wang, J., Tao, C., & Ren, Q , et al. (2013). Optimizing chinese character displays improves recognition and reading performance of simulated irregular phosphene maps. Invest Ophthalmol Vis Sci, 54(4), 2918-2926.
  32. Cao, P., Sun, J., Yan, Y., Yao, C., Chai, X., & Sun, X., & Ren, Q et al. (2015). Properties of electrically evoked potentials activated by optic nerve stimulation with penetrating electrodes of different modes in rabbits. Graefes Archive for Clinical & Experimental Ophthalmology, 253(12), 2171-2180.
  33. Yan Y, Lu Y, Li M, Ma Z, Cao P, Chen Y, Sun X, Chai X, Ren Q, Li L. Electrically Evoked Responses in the Rabbit Cortex Induced by Current Steering With Penetrating Optic Nerve Electrodes [J]. Investigative Ophthalmology & Visual Science, 2016, 57(14): 6327-38.

Biomedical Optics and Laser Medicine

  1. RA Hill, QS Ren, DC Nguyen, et al. Free-Electron laser (FEL) Ablation of Ocular TissuesLASERS IN MEDICAL SCIENCE, 13(3): 219-226, 1998.
  2. Dang Yongyan, Ren Qiushi, Liu Huaxu, Ma Jingbo, Zhang Jinsheng. Effects of the 1,320-nm Nd : YAG laser on transepidermal water loss, histological changes, and collagen remodeling in skin. Lasers in Medical Science, 21(3):147-152(6), 2006.
  3. Dang Yongyan, Ren Qiushi, Li Wanrong, Yang Qing & Zhang Jinsheng. Comparison of biophysical properties of skin measured by using non-invasive techniques in the KM mice following 595 nm pulsed dye, 1064 nm Q-Switched Nd:YAG and 1320 nm Nd:YAG laser non-ablative rejuvenation. Skin Research and Technology, 12 (2):119-125, 2006.
  4. H Liu, Y Dang, X Chai, Z Wang, L Ma, Q Ren. Treatment of port wines stains with 595nm pulsed dye laser: a pilot study in Chinese patients. Clinical and experimental dermatology, 32(6): 646-649, 2007.
  5. Huaxu Liu and Yongyan Dang, Zhan Wang, Xinyu Chai and Qiushi Ren. Laser Induced Collagen Remodeling: A Comparative Study In Vivo on Mouse Model. lasers in surgery and medicine, 40(1):13-19, 2008.
  6. Cheng Wang, Jin Fan, Qiushi RenVisible light reflectance spectrum for measurement of cancerous tissue. SPECTROSCOPY AND SPECTRAL ANALYSIS, 28(1):33-36,2008
  7. W. Wang, K. Zhang, Q. Ren and J.U. Kang. Comparison of different focusing systems for common-path optical coherence tomography with fiber-optic bundle as endoscopic probe. Optical Engineering, 48(10):103001, 2009.
  8. W. Wang, Y. Liu, P. Xi, Q. Ren. The origin and effect of high-order dispersion in ultrashort pulse multiphoton microscopy in 10 femtosecond regime. Applied Optics, 49(35):6703-6709, 2010.
  9. H. Wang, X. Xu, X. Li, P. Xi*, Q. Ren. Systematic design of a cross-polarized dermoscope for visual inspection and digital imaging. IEEE Instrumentation and Measurement Magazine, 14(6):26-31, 2011.
  10. HUANG Zhen, ZHOU Dai, REN Qiu-shi,  Biomechanical Properties and Modeling of Skin with Laser Influence, Journal of Shanghai Jiaotong University(Science), 2011, 16(5): 610-613.
  11. Shuoqi Ye, Ran Yang, Jingwei Xiong, K. Kirk Shung, Qifa Zhou, Changhui Li, and Qiushi Ren. Label-free imaging of zebrafish larvae in vivo by photoacoustic microscopy. Biomedical Optics Express, 3(2): 360-365, 2012.
  12. Y. Ding, H. Xie, T. Peng, Y. Lu, D. Jin, J. Teng, Q. Ren, P. Xi*. Laser Oblique Scanning Optical Microscopy (LOSOM) for Phase Relief Imaging. Optics Express, 20 (13): 14100-14108, 2012.
  13. Zhao Q, Zhou C*, Wei H, He Y, Chai X, Ren Q. Ex vivo determination of glucose permeability and optical attenuation coefficient in normal and adenomatous human colon tissues using spectral domain optical coherence tomography. Journal of Biomedical Optics. 17(10):105004, 2012.
  14. Jiang X, Ge H, Zhou C, Chai X and Ren Q. The role of vascular endothelial growth factor in fractional laser resurfacing with the carbon dioxide laser. Lasers in Medical Science. 27(3):599-606, 2012.
  15. Xia Jiang, Hongmei Ge, Jianjun Liu, Qiu Shi Ren. Fractional scanned carbon dioxide laser induces collagen remodeling in murine dermis. Laser Physics. 2011; 21(3):548-553
  16. Shuoqi Ye, Junyu Yang, Jianzhong Xi, Qiushi Ren, and Changhui Li. Studying of murine hindlimb ischemia by photoacoustic microscopy. Chinese Optics Letters. 2012, 10(12): 121701-121701.
  17. T. Peng, H. Xie, Y. Ding, W. Wang, Z. Li, D. Jin, Y. Tang, Q. Ren, P. Xi*. CRAFT: multimodality confocal skin imaging for early cancer diagnosis. Journal of Biophotonics, 5(5-6):469-476, 2012.
  18. Zhao, Q., Zhou, C., Wei, H., He, Y., Chai, X., & Ren, Q. (2012). Ex vivo determination of glucose permeability and optical attenuation coefficient in normal and adenomatous human colon tissues using spectral domain optical coherence tomography. Journal of Biomedical Optics, 17(10), 105004-105001.
  19. Deng, Z., Zhao, H., Ren, Q., & Li, C. (2013). Acoustically penetrable optical reflector for photoacoustic tomography. Journal of Biomedical Optics, 18(7), 070503.
  20. Ding, Y., Zhang, Y., Peng, T., Lu, Y., Jin, D., & Ren, Q., et al. (2013). Observation of mesenteric microcirculatory disturbance in rat by laser oblique scanning optical microscopy. Scientific Reports, 3(5), 1762.
  21. Zhao, Q., Li, L., Li, Q., Jiang, X., Ren, Q., & Chai, X., et al. (2014). Concentration dependence of optical clearing on the enhancement of laser-scanning optical-resolution photoacoustic microscopy imaging. Journal of biomedical optics, 19(3), 36019.
  22. Zhao, Q., Wei, H., He, Y., Ren, Q., & Zhou, C. (2014). Evaluation of ultrasound and glucose synergy effect on the optical clearing and light penetration for human colon tissue using SD-OCT. Journal of Biophotonics, 7(11‐12), 938-947.
  23. Ding, Y., Zhang, M., Lang, J., Leng, J., Ren, Q., & Yang, J., et al. (2015). In vivo study of endometriosis in mice by photoacoustic microscopy. Journal of Biophotonics, 8(1-2), 94.
  24. Zhe Jiang, Zekuan Yu, Yue Yu, Zhiyu Huang, Qiushi Ren, Changhui Li. Spatial resolution enhancement for pushbroom-based microscopic hyperspectral imaging [J]. Applied Optics, 2019, 58(4): 850-62.
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